Cardiac toxicity of PAMAM dendrimer drug delivery systems can be attenuated with the adjunct use of cardioprotective agents. Biomolecules and Biomedicine 2024 |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
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2024 |
Targeting the Epidermal Growth Factor Receptor (EGFR/ErbB) for the potential treatment of renal pathologies. Frontiers in Pharmacology, Renal Pharmacology, 2024 |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
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2024 |
Mitigating Cardiotoxicity of
Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced
Cardiac Dysfunction in the Isolated Mammalian Heart. Pharmaceutics. 2022 14(12):2673. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
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2022 |
The Role of Epidermal
Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating
Diabetes-Induced Cardiovascular Complications. Front Pharmacol. 2021 12:701390. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
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2021 |
Emerging innate biological properties of nano-drug delivery systems: A focus on
PAMAM dendrimers and their clinical potential. Adv Drug Deliv Rev. 2021 178:113908. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2021 |
Nanotoxicology of Dendrimers in the Mammalian
Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs
Recovery of Cardiac Function Following Ischemia-Reperfusion Injury. Int J
Nanomedicine. 2020 15:4393-4405. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2020 |
Pharmacotherapy
in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety.
J Drug Target. 2020 28(7-8):683-699. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2020 |
Chronic administration of nano-sized PAMAM dendrimers in vivo inhibits EGFR-
ERK1/2-ROCK signaling pathway and attenuates diabetes-induced vascular
remodeling and dysfunction.
Nanomedicine. 2019 18:78-89. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2019 |
Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation
via blockade of Src-mediated EGFR transactivation in a murine model of asthma.
PLoS One. 2019 14(11):e0224163. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2019 |
Src-dependent EGFR transactivation regulates lung inflammation via
downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine
asthma model. Sci Rep. 2017 7(1):9919. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2017 |
Angiotensin-(1-7)
Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus
Cavernosum. Biomed Res Int. 2017:5084961. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2017 |
Angiotensin-(1-7)-dependent
vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin
receptor selectivity. Peptides. 2017 90:10-16. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2017 |
Naked
Polyamidoamine Polymers Intrinsically Inhibit Angiotensin II-Mediated EGFR and
ErbB2 Transactivation in a Dendrimer Generation- and Surface Chemistry-Dependent Manner.
Molecular Pharmacology 2016 13(5):1575-86. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2016 |
Endogenous angiotensin-(1-7)/Mas
receptor/NO pathway mediates the cardioprotective effects of pacing postconditioning.
American Journal of Physiology Heart Circ Physiol. 2016 310(1):H104-12. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2016 |
Impact of PAMAM delivery systems on signal transduction pathways in vivo:
Modulation of ERK1/2 and p38 MAP kinase signaling in the normal and diabetic
kidney. Int J Pharm. 2016 514(2):353-363. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2016 |
Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.
PLoS One. 2015 10(7):e0132215. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2015 |
Transactivation of ErbB Family of Receptor Tyrosine Kinases Is Inhibited by
Angiotensin-(1-7) via Its Mas Receptor.
PLoS One. 2015 10(11):e0141657. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2015 |
The dual targeting of EGFR and ErbB2 with the inhibitor
Lapatinib corrects high glucose-induced apoptosis and vascular dysfunction by
opposing multiple diabetes-induced signaling changes. J Drug Target.
2015;23(6):506-18. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2015 |
Chronic treatment
with Ang-(1-7) reverses abnormal reactivity in the corpus cavernosum and
normalizes diabetes-induced changes in the protein levels of ACE, ACE2, ROCK1,
ROCK2 and omega-hydroxylase in a rat model of type 1 diabetes. J Diabetes Res.
2014;2014:142154. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2014 |
Activation of ErbB2 and Downstream Signalling via Rho Kinases and
ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction. PLoS One. 2013 8(6):e67813. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2013 |
Chronic treatment
with LY294002, an inhibitor of phosphatidylinositol 3-kinase, attenuates
ischemia/reperfusion-induced cardiac dysfunction in normotensive and
hypertensive diabetic animals. Mol Cell Biochem. 2013 373(1-2):259-64. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2013 |
Role of
angiotensin II and angiotensin-(1-7) in diabetes-induced oxidative DNA damage in
the corpus cavernosum. Fertil Steril. 2013 100(1):226-33. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2013 |
RU28318, an
aldosterone antagonist, in combination with an ACE inhibitor and angiotensin
receptor blocker attenuates cardiac dysfunction in diabetes. J Diabetes Res.
2013;2013:427693. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2013 |
The role of epidermal growth factor receptor in
diabetes-induced cardiac dysfunction. Bioimpacts. 2013;3(1):5-9. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2013 |
On the
nanotoxicity of PAMAM dendrimers: Superfect® stimulates the EGFR-ERK1/2 signal
transduction pathway via an oxidative stress-dependent mechanism in HEK 293
cells. Int J Pharm. 2013 448(1):239-46. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2013 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an
experimental model of type-1 diabetes. Pharmacol Res. 2012 66(3):269-75. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2012 |
Activation of EGFR/ERBB2
via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of
diabetic hearts from ischemia-reperfusion injury. PLoS One. 2012;7(6):e39066. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2012 |
Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via
a Mas receptor-dependent pathway. British Journal of Pharmacology 2012 165(5):1390-400. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2012 |
Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through
suppression of ERK1/2- and NF-κB-dependent pathways.
British Journal of Pharmacology 2012 Jul;166(6):1964-76. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2012 |
Angiotensin-(1-7) via the mas receptor alleviates the diabetes-induced decrease
in GFAP and GAP-43 immunoreactivity with concomitant reduction in the COX-2 in
hippocampal formation: an immunohistochemical study. Cell Mol Neurobiol. 2012
32(8):1323-36. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2012 |
Inhibition
of Ras-GTPase farnesylation and the ubiquitin-proteasome system or treatment
with angiotensin-(1-7) attenuates spinal cord injury-induced cardiac
dysfunction. J Neurotrauma. 2011 28(7):1271-9. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2011 |
Effect of
inhibition of the ubiquitin-proteasome-system and IκB kinase on airway
inflammation and hyperresponsiveness in a murine model of asthma. Int J Immunopathol Pharmacol. 2011 24(1):33-42. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced
cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester. J Cardiovasc Pharmacol. 2011 57(5):559-67. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2011 |
Role of 20-hydroxyeicosatetraenoic and
epoxyeicosatrienoic acids in the regulation of vascular function in a model of hypertension and endothelial dysfunction. Pharmacology. 2010;86(3):149-56. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2010 |
Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities. European Journal of Pharmacology 2010 638(1-3):108-14. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2010 |
FPTIII mitigates peroxisome-mediated
oxidative stress in kidneys of spontaneously hypertensive diabetic rats. Kidney Blood Press Res. 2010;33(1):60-5. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2010 |
Early
inhibition of EGFR signaling prevents diabetes-induced up-regulation of multiple
gene pathways in the mesenteric vasculature. Vascul Pharmacol. 2009 51(4):236-45. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2009 |
Role of
epidermal growth factor receptor (EGFR) in corneal remodelling in diabetes. Acta Ophthalmol. 2009 87(8):881-9. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2009 |
Global
upregulation of gene expression associated with renal dysfunction in DOCA-salt-
induced hypertensive rats occurs via signaling cascades involving epidermal
growth factor receptor: a microarray analysis. Vascular Pharmacology 2009 51(2-3):101-9. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2009 |
Cytochrome P450 metabolites of arachidonic
acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury. Auton Autacoid Pharmacol. 2009 29(1-2):33-41. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2009 |
Role of
20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.
Auton Autacoid Pharmacol. 2009 29(1-2):1-12. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2009 |
Endogenous angiotensin-(1-7) reduces
cardiac ischemia-induced dysfunction in diabetic hypertensive rats. Pharmacological Research 2009 59(4):263-8. |
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities) |
|
2009 |